UVRAG

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
UVRAG p63,VPS38 UV radiation resistance associated NM_003369 pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Differential expression in human EBOV infected cells. Interesting pattern in bats also.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome50 43 49 37 75 211 46 44 37
Read_Max
batR. aegyptiacusTranscriptome 120 131 65 93 84 124 81 121 105
Read_Max
bat_genomeR. aegyptiacusGenome 129 93 57 116 67 68 68 145 117
DESeq
humanH. sapiensGenome 645.39 738.37 788.31 715.07 839.15 2740.75 672.94 559.75 766.49
DESeq
batR. aegyptiacusTranscriptome 768.05 830.63 650.86 736.28 845.31 1019.85 736.3 785.9 755.0
DESeq
bat_genomeR. aegyptiacusGenome 1112.91 986.61 906.01 1180.04 1112.79 1437.26 1112.16 1033.21 1034.28

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 645.39 715.07 672.94 0.15 0.06 -0.09
7h 738.37 839.15 559.75 0.18 -0.4 -0.58
23h 788.31 2740.75 766.49 1.8 -0.04 -1.84

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 645.39 738.37 788.31 0.19 0.29 0.09
Ebov 715.07 839.15 2740.75 0.23 1.94 1.71
Marv 672.94 559.75 766.49 -0.27 0.19 0.45

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 768.05 736.28 736.3 -0.06 -0.06 0.0
7h 830.63 845.31 785.9 0.03 -0.08 -0.11
23h 650.86 1019.85 755.0 0.65 0.21 -0.43

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 768.05 830.63 650.86 0.11 -0.24 -0.35
Ebov 736.28 845.31 1019.85 0.2 0.47 0.27
Marv 736.3 785.9 755.0 0.09 0.04 -0.06