LAMB2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
LAMB2 LAMS,NPHS5 laminin, beta 2 (laminin S) NM_002292 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

LAMB2 is one of several genes associated with congenital nephrotic syndrome.LAMB2 encodes the basement membrane protein laminin beta2, which is incorporated in specific heterotrimeric laminin isoforms and has an expression pattern corresponding to the pattern of organ manifestations in Pierson syndrome.Mutations of LAMB2 typically cause autosomal recessive Pierson syndrome, a disorder characterized by congenital nephrotic syndrome, ocular and neurologic abnormalities, but may occasionally be associated with milder or oligosymptomatic disease variants.

In our dateset, LAMB2 was observed to be a little bit up-regulated by Eobla virus (23 h) in human cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome66 147 83 132 156 312 172 210 83
Read_Max
batR. aegyptiacusTranscriptome 58 68 53 70 49 73 42 72 59
Read_Max
bat_genomeR. aegyptiacusGenome 180 135 112 156 118 71 102 202 196
DESeq
humanH. sapiensGenome 1634.81 3589.93 2048.2 2848.15 2776.41 7187.25 3122.97 3562.91 1928.87
DESeq
batR. aegyptiacusTranscriptome 1128.47 1333.49 1328.81 1113.54 1091.71 1077.59 969.91 1184.13 1216.85
DESeq
bat_genomeR. aegyptiacusGenome 2679.58 2639.48 2788.33 3282.4 2621.8 2544.24 2331.15 2784.83 2856.26

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1634.81 2848.15 3122.97 0.8 0.93 0.13
7h 3589.93 2776.41 3562.91 -0.37 -0.01 0.36
23h 2048.2 7187.25 1928.87 1.81 -0.09 -1.9

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1634.81 3589.93 2048.2 1.13 0.33 -0.81
Ebov 2848.15 2776.41 7187.25 -0.04 1.34 1.37
Marv 3122.97 3562.91 1928.87 0.19 -0.7 -0.89

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1128.47 1113.54 969.91 -0.02 -0.22 -0.2
7h 1333.49 1091.71 1184.13 -0.29 -0.17 0.12
23h 1328.81 1077.59 1216.85 -0.3 -0.13 0.18

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1128.47 1333.49 1328.81 0.24 0.24 -0.01
Ebov 1113.54 1091.71 1077.59 -0.03 -0.05 -0.02
Marv 969.91 1184.13 1216.85 0.29 0.33 0.04