HNRNPR

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
HNRNPR	HNRNPR, HNRPR, hnRNP-R,hnRNP-R	heterogeneous nuclear ribonucleoprotein R	NM_005826	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes an RNA-binding protein that is a member of thespliceosome C complex, which functions in pre-mRNA processing andtransport. The encoded protein also promotes transcription at the c-fosgene. Alternative splicing results in multiple transcript variants.

For human cells Ebola and Marburg infected cells, a slight downregulation at 23hours can be observed. In bat cells homologs show constant expression levels.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	921	785	836	1056	1214	305	1280	1075	725
Read_Max	R. aegyptiacus	Transcriptome	1037	856	649	998	831	548	834	1153	879
Read_Max	R. aegyptiacus	Genome	1148	1062	577	969	709	349	708	1372	1110
DESeq	H. sapiens	Genome	9043.77	8553.65	8976.13	10558.02	8553.24	2843.39	10611.67	8636.38	7726.6
DESeq	R. aegyptiacus	Transcriptome	8150.36	8223.76	6994.3	7861.1	7702.77	5056.74	8034.8	8093.71	6959.31
DESeq	R. aegyptiacus	Genome	9562.43	9164.27	7591.75	10209.59	9135.56	6087.13	9397.71	9095.09	8067.04

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	9043.77	10558.02	10611.67	0.22	0.23	0.01
7h	8553.65	8553.24	8636.38	0.0	0.01	0.01
23h	8976.13	2843.39	7726.6	-1.66	-0.22	1.44

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	9043.77	8553.65	8976.13	-0.08	-0.01	0.07
Ebov	10558.02	8553.24	2843.39	-0.3	-1.89	-1.59
Marv	10611.67	8636.38	7726.6	-0.3	-0.46	-0.16

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	8150.36	7861.1	8034.8	-0.05	-0.02	0.03
7h	8223.76	7702.77	8093.71	-0.09	-0.02	0.07
23h	6994.3	5056.74	6959.31	-0.47	-0.01	0.46

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	8150.36	8223.76	6994.3	0.01	-0.22	-0.23
Ebov	7861.1	7702.77	5056.74	-0.03	-0.64	-0.61
Marv	8034.8	8093.71	6959.31	0.01	-0.21	-0.22

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material