DUSP16
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| DUSP16 | DUSP16, MKP-7, MKP7,MKP-7, KIAA1700 | dual specificity phosphatase 16 | NM_030640 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
his gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.
Its expression seems to be constantly upregulated in the course of Ebola infection in human cells and bat cells cells. Different modulation for Marburg and mock treated cells can be observed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 176 | 168 | 195 | 176 | 278 | 736 | 262 | 269 | 278 |
Read_Max |  | R. aegyptiacus | Transcriptome | 165 | 136 | 170 | 163 | 124 | 253 | 144 | 186 | 193 |
Read_Max |  | R. aegyptiacus | Genome | 176 | 160 | 129 | 130 | 107 | 133 | 107 | 217 | 204 |
DESeq | | H. sapiens | Genome | 3483.75 | 3303.35 | 3066.84 | 3546.24 | 3318.65 | 11270.56 | 3537.01 | 3454.19 | 5075.65 |
DESeq | | R. aegyptiacus | Transcriptome | 1460.32 | 1280.84 | 1458.29 | 1323.23 | 1478.28 | 2092.59 | 1400.41 | 1288.23 | 1415.4 |
DESeq | | R. aegyptiacus | Genome | 2668.41 | 2555.52 | 2656.67 | 2535.86 | 2898.6 | 4234.75 | 2906.92 | 2520.78 | 2924.75 |