TRIM6
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| TRIM6 | A8K2A7, NM_058166, NP_001185574, Q86WZ8, Q9C030, Q9HCR1, RNF89, TRIM6_HUMAN,RNF89 | tripartite motif containing 6 | NM_001003818 |  |
 |
 |
 |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members.
This gene was slightly differential expressed. The strongest regulation was found for the EBOV-infected cell between 7 h and 23 h p.i. with a twofold downregulation.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 80 | 89 | 120 | 86 | 106 | 62 | 112 | 132 | 155 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Read_Max |  | R. aegyptiacus | Genome | 30 | 27 | 24 | 25 | 29 | 21 | 22 | 57 | 50 |
DESeq | | H. sapiens | Genome | 967.08 | 1075.95 | 1517.04 | 1153.09 | 1206.61 | 624.75 | 1180.84 | 1074.53 | 2232.24 |
DESeq | | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | R. aegyptiacus | Genome | 236.33 | 335.87 | 305.72 | 237.0 | 362.74 | 279.36 | 291.25 | 371.89 | 464.06 |