UBR4
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| UBR4 | RBAF600, ZUBR1, p600,KIAA1307, KIAA0462, RBAF600 | ubiquitin protein ligase E3 component n-recognin 4 | NM_020765 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein.Moderately high expression with upregulation in EBOV infection in human, and MARV infection in bat.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 111 | 112 | 125 | 94 | 154 | 426 | 127 | 124 | 132 |
Read_Max |  | R. aegyptiacus | Transcriptome | 147 | 98 | 85 | 88 | 90 | 153 | 73 | 95 | 172 |
Read_Max |  | R. aegyptiacus | Genome | 148 | 85 | 73 | 91 | 72 | 93 | 56 | 110 | 176 |
DESeq | | H. sapiens | Genome | 7329.79 | 8918.77 | 9649.27 | 8151.18 | 9236.12 | 28936.81 | 7382.68 | 7648.39 | 9971.97 |
DESeq | | R. aegyptiacus | Transcriptome | 5387.98 | 4717.36 | 5347.67 | 4997.8 | 5472.07 | 7748.85 | 5065.78 | 4155.18 | 5216.89 |
DESeq | | R. aegyptiacus | Genome | 5085.87 | 4416.48 | 4843.59 | 4683.63 | 4816.12 | 7171.92 | 4699.42 | 3645.17 | 4539.53 |