MAFG
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| MAFG | MGC13090, MGC20149 | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | NM_002359 |  |
 |
 |
 |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 (PubMed 9166829)). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490)II. Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).
This gene is upregulated in Ebola infected cells after 7 h and 23 h.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 128 | 127 | 113 | 86 | 174 | 465 | 174 | 244 | 204 |
Read_Max |  | R. aegyptiacus | Transcriptome | 99 | 85 | 75 | 87 | 91 | 128 | 62 | 128 | 198 |
Read_Max |  | R. aegyptiacus | Genome | 120 | 93 | 65 | 84 | 75 | 80 | 59 | 155 | 232 |
DESeq | | H. sapiens | Genome | 2380.68 | 2298.77 | 2485.05 | 2153.47 | 2489.44 | 7501.76 | 3035.25 | 3777.93 | 4249.26 |
DESeq | | R. aegyptiacus | Transcriptome | 241.28 | 282.38 | 307.61 | 365.44 | 354.71 | 498.87 | 289.11 | 360.4 | 566.06 |
DESeq | | R. aegyptiacus | Genome | 696.11 | 840.58 | 830.14 | 753.45 | 879.51 | 1362.85 | 730.95 | 889.69 | 1495.77 |