EPS8

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
EPS8		epidermal growth factor receptor pathway substrate 8		pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. If binds to EGF receptor/EGFR enhances EGF-dependent mitogenic signals Not a visible change on expression, but might have differentially spliced exons, which were not annotated.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	212	176	265	199	262	650	247	241	220
Read_Max	R. aegyptiacus	Transcriptome	342	253	194	233	206	225	209	252	261
Read_Max	R. aegyptiacus	Genome	389	244	164	236	177	129	179	315	278
DESeq	H. sapiens	Genome	2961.13	2569.04	3259.45	3093.39	2781.29	9091.39	3050.16	2607.68	3768.66
DESeq	R. aegyptiacus	Transcriptome	3214.54	2965.51	2174.11	2842.32	2824.14	2838.11	3086.81	2796.89	2493.92
DESeq	R. aegyptiacus	Genome	3788.19	3375.11	2462.52	3666.53	3503.54	3481.53	3716.58	3318.48	2954.72

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2961.13	3093.39	3050.16	0.06	0.04	-0.02
7h	2569.04	2781.29	2607.68	0.11	0.02	-0.09
23h	3259.45	9091.39	3768.66	1.48	0.21	-1.27

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2961.13	2569.04	3259.45	-0.2	0.14	0.34
Ebov	3093.39	2781.29	9091.39	-0.15	1.56	1.71
Marv	3050.16	2607.68	3768.66	-0.23	0.31	0.53

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3214.54	2842.32	3086.81	-0.18	-0.06	0.12
7h	2965.51	2824.14	2796.89	-0.07	-0.08	-0.01
23h	2174.11	2838.11	2493.92	0.38	0.2	-0.19

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3214.54	2965.51	2174.11	-0.12	-0.56	-0.45
Ebov	2842.32	2824.14	2838.11	-0.01	-0.0	0.01
Marv	3086.81	2796.89	2493.92	-0.14	-0.31	-0.17

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material