BCL3
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| BCL3 | B-cell CLL/lymphoma 3 | NM_005178 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. The gene has a moderate expression, which does not differ much in the different samples. After Marburg virus infection, the expression decreases slightly in Hu7, whereas expression increases slightly in bat.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 48 | 37 | 21 | 36 | 43 | 94 | 64 | 48 | 23 |
Read_Max |  | R. aegyptiacus | Transcriptome | 43 | 35 | 51 | 33 | 32 | 36 | 19 | 37 | 59 |
Read_Max |  | R. aegyptiacus | Genome | 42 | 36 | 42 | 34 | 22 | 30 | 20 | 44 | 67 |
DESeq | | H. sapiens | Genome | 488.1 | 370.19 | 220.41 | 397.96 | 288.78 | 720.81 | 357.15 | 365.5 | 281.54 |
DESeq | | R. aegyptiacus | Transcriptome | 235.4 | 193.43 | 466.41 | 239.99 | 194.83 | 350.03 | 173.42 | 187.72 | 378.87 |
DESeq | | R. aegyptiacus | Genome | 334.3 | 344.99 | 753.15 | 295.26 | 275.69 | 535.22 | 249.65 | 298.15 | 531.7 |