DEPTOR

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
DEPTOR	B2RCL9, DEPDC6, DPTOR_HUMAN, NM_022783, NP_073620, Q8TB45, Q96EQ1, Q9H0R7, Q9H894, Q9HA07,DEP.6, FLJ12428	DEP domain containing MTOR-interacting protein	NM_022783	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens DEP domain containing MTOR-interacting protein (DEPTOR) is negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.

This gene is slight expressed in HG19. HG19 MOCK 23h shows a 2 fold increase of transcripts, while all other samples stay on the same level. RAE dosn't show any expression.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	28	26	51	29	35	21	29	37	39
Read_Max	R. aegyptiacus	Transcriptome	2	3	3	6	7	4	2	5	2
Read_Max	R. aegyptiacus	Genome	5	7	3	4	6	3	2	5	5
DESeq	H. sapiens	Genome	209.03	223.33	474.58	208.6	217.24	148.38	193.11	190.45	343.51
DESeq	R. aegyptiacus	Transcriptome	7.72	12.8	20.54	18.4	24.0	11.27	9.9	16.7	7.12
DESeq	R. aegyptiacus	Genome	26.64	31.03	31.24	31.6	34.6	22.19	20.24	36.48	20.55

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	209.03	208.6	193.11	-0.0	-0.11	-0.11
7h	223.33	217.24	190.45	-0.04	-0.23	-0.19
23h	474.58	148.38	343.51	-1.68	-0.47	1.21

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	209.03	223.33	474.58	0.1	1.18	1.09
Ebov	208.6	217.24	148.38	0.06	-0.49	-0.55
Marv	193.11	190.45	343.51	-0.02	0.83	0.85

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	7.72	18.4	9.9	1.25	0.36	-0.89
7h	12.8	24.0	16.7	0.91	0.38	-0.52
23h	20.54	11.27	7.12	-0.87	-1.53	-0.66

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	7.72	12.8	20.54	0.73	1.41	0.68
Ebov	18.4	24.0	11.27	0.38	-0.71	-1.09
Marv	9.9	16.7	7.12	0.75	-0.48	-1.23

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material