FGA

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
FGA fibrinogen alpha chain NM_000508 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is the alpha component of fibrinogen, which is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Also, acts as a cofactor in platelet aggregation. Very low expression in bats, and highly express in humans. In both viral treatments in humans the expression of this genes decreases at least 3 folds.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome4298 5142 4458 5045 7455 1979 6066 6349 2600
Read_Max
batR. aegyptiacusTranscriptome 11 8 6 15 12 9 17 11 10
Read_Max
bat_genomeR. aegyptiacusGenome 0 0 0 0 0 0 0 0 0
DESeq
humanH. sapiensGenome 46402.13 47672.92 41668.86 51624.9 50783.59 16418.45 50173.61 48284.96 25797.22
DESeq
batR. aegyptiacusTranscriptome 34.61 37.31 54.75 43.12 25.09 36.93 100.0 51.4 42.99
DESeq
bat_genomeR. aegyptiacusGenome 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 46402.13 51624.9 50173.61 0.15 0.11 -0.04
7h 47672.92 50783.59 48284.96 0.09 0.02 -0.07
23h 41668.86 16418.45 25797.22 -1.34 -0.69 0.65

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 46402.13 47672.92 41668.86 0.04 -0.16 -0.19
Ebov 51624.9 50783.59 16418.45 -0.02 -1.65 -1.63
Marv 50173.61 48284.96 25797.22 -0.06 -0.96 -0.9

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 34.61 43.12 100.0 0.32 1.53 1.21
7h 37.31 25.09 51.4 -0.57 0.46 1.03
23h 54.75 36.93 42.99 -0.57 -0.35 0.22

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 34.61 37.31 54.75 0.11 0.66 0.55
Ebov 43.12 25.09 36.93 -0.78 -0.22 0.56
Marv 100.0 51.4 42.99 -0.96 -1.22 -0.26