ACSL4

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
ACSL4	LACS4,ACS4, LACS4	acyl-CoA synthetase long-chain family member 4	NM_004458	pdf			NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Sashimi expanded look shows a small difference in the first splicing motif in mock, relative to viral infected strain in human.

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source		Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max		H. sapiens	Genome	2301	2342	2526	2147	3251	1103	2573	2907	1630
Read_Max		R. aegyptiacus	Transcriptome	1124	897	680	1042	825	1233	851	1130	1226
Read_Max		R. aegyptiacus	Genome	1202	997	514	808	639	683	698	1257	1268
DESeq		H. sapiens	Genome	44045.79	44204.33	52232.51	43007.03	52130.65	16867.17	40491.9	41080.42	38157.09
DESeq		R. aegyptiacus	Transcriptome	10331.37	9146.88	8989.07	10813.21	10517.15	13466.71	10783.55	10474.84	11152.66
DESeq		R. aegyptiacus	Genome	15294.56	15376.0	11585.12	14019.3	15331.21	19509.35	15684.97	14489.5	15521.9

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	44045.79	43007.03	40491.9	-0.03	-0.12	-0.09
7h	44204.33	52130.65	41080.42	0.24	-0.11	-0.34
23h	52232.51	16867.17	38157.09	-1.63	-0.45	1.18

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	44045.79	44204.33	52232.51	0.01	0.25	0.24
Ebov	43007.03	52130.65	16867.17	0.28	-1.35	-1.63
Marv	40491.9	41080.42	38157.09	0.02	-0.09	-0.11

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	10331.37	10813.21	10783.55	0.07	0.06	-0.0
7h	9146.88	10517.15	10474.84	0.2	0.2	-0.01
23h	8989.07	13466.71	11152.66	0.58	0.31	-0.27

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	10331.37	9146.88	8989.07	-0.18	-0.2	-0.03
Ebov	10813.21	10517.15	13466.71	-0.04	0.32	0.36
Marv	10783.55	10474.84	11152.66	-0.04	0.05	0.09