WASF2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| WASF2 | WAVE2, SCAR2 | WAS protein family, member 2 | NM_006990 |  |
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Description
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. WASF2 is almost 3 fold upregulated in 23h EBOV in human. The bat homolog is upregulated in MARV 23h.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 191 | 211 | 239 | 213 | 287 | 955 | 215 | 289 | 329 |
Read_Max |  | R. aegyptiacus | Transcriptome | 584 | 463 | 403 | 418 | 353 | 620 | 387 | 488 | 682 |
Read_Max |  | R. aegyptiacus | Genome | 609 | 398 | 332 | 428 | 298 | 337 | 316 | 520 | 700 |
DESeq | | H. sapiens | Genome | 3847.04 | 3694.98 | 4069.6 | 3786.93 | 3689.36 | 11361.36 | 3439.64 | 3883.45 | 6248.9 |
DESeq | | R. aegyptiacus | Transcriptome | 3388.45 | 3097.13 | 3186.77 | 2924.73 | 2797.86 | 3842.85 | 3052.33 | 2836.55 | 3666.03 |
DESeq | | R. aegyptiacus | Genome | 7919.28 | 6418.91 | 7062.87 | 7556.22 | 7062.9 | 9619.57 | 7934.7 | 6513.26 | 8828.19 |