PPRC1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
PPRC1	PRC, KIAA0595, MGC74642	peroxisome proliferator-activated receptor gamma, coactivator-related 1	NM_015062	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes. Interesting alternative splicing and expression profiles in infected cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	137	190	184	192	225	549	245	308	154
Read_Max	R. aegyptiacus	Transcriptome	118	143	97	132	117	150	84	148	126
Read_Max	R. aegyptiacus	Genome	175	196	125	146	133	127	83	265	202
DESeq	H. sapiens	Genome	3992.16	4727.09	3847.2	5090.73	3795.85	11321.88	5493.18	5871.43	3777.36
DESeq	R. aegyptiacus	Transcriptome	2499.58	2550.7	2281.61	2571.28	2464.95	3179.44	1964.4	2497.8	2337.35
DESeq	R. aegyptiacus	Genome	3075.76	3324.91	2841.89	3327.82	3259.11	3959.31	2437.99	3140.07	2929.89

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3992.16	5090.73	5493.18	0.35	0.46	0.11
7h	4727.09	3795.85	5871.43	-0.32	0.31	0.63
23h	3847.2	11321.88	3777.36	1.56	-0.03	-1.58

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3992.16	4727.09	3847.2	0.24	-0.05	-0.3
Ebov	5090.73	3795.85	11321.88	-0.42	1.15	1.58
Marv	5493.18	5871.43	3777.36	0.1	-0.54	-0.64

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2499.58	2571.28	1964.4	0.04	-0.35	-0.39
7h	2550.7	2464.95	2497.8	-0.05	-0.03	0.02
23h	2281.61	3179.44	2337.35	0.48	0.03	-0.44

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2499.58	2550.7	2281.61	0.03	-0.13	-0.16
Ebov	2571.28	2464.95	3179.44	-0.06	0.31	0.37
Marv	1964.4	2497.8	2337.35	0.35	0.25	-0.1

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material