LAMA5

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
LAMA5		laminin, alpha 5	NM_005560	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The laminin, alpha 5 gene is involved in the PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Toxoplasmosis, Amoebiasis, Pathways in cancer and Small cell lung cancer.

In bat it seems to be slightly downregulated in ebola infection and slightly upregulated during marburg virus infection. No change in human.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	55	77	69	61	93	195	74	124	68
Read_Max	R. aegyptiacus	Transcriptome	44	48	41	42	45	70	35	55	74
Read_Max	R. aegyptiacus	Genome	168	146	117	124	98	89	91	194	292
DESeq	H. sapiens	Genome	3441.13	3969.33	3730.05	3492.63	3769.03	9912.53	3776.49	4204.78	4006.79
DESeq	R. aegyptiacus	Transcriptome	1636.75	1565.86	2287.72	1890.94	1989.68	2211.92	1627.34	1863.27	2601.51
DESeq	R. aegyptiacus	Genome	6405.89	7642.82	8734.31	6458.14	7547.3	8161.42	5793.59	7211.05	9876.17

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3441.13	3492.63	3776.49	0.02	0.13	0.11
7h	3969.33	3769.03	4204.78	-0.07	0.08	0.16
23h	3730.05	9912.53	4006.79	1.41	0.1	-1.31

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3441.13	3969.33	3730.05	0.21	0.12	-0.09
Ebov	3492.63	3769.03	9912.53	0.11	1.5	1.4
Marv	3776.49	4204.78	4006.79	0.15	0.09	-0.07

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1636.75	1890.94	1627.34	0.21	-0.01	-0.22
7h	1565.86	1989.68	1863.27	0.35	0.25	-0.09
23h	2287.72	2211.92	2601.51	-0.05	0.19	0.23

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1636.75	1565.86	2287.72	-0.06	0.48	0.55
Ebov	1890.94	1989.68	2211.92	0.07	0.23	0.15
Marv	1627.34	1863.27	2601.51	0.2	0.68	0.48

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material