ZC3H7B

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
ZC3H7B	RoXaN, FLJ13787, DKFZp434K0920, KIAA1031	zinc finger CCCH-type containing 7B	NM_017590	pdf

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Description

The zinc finger CCCH-type containing 7B gene is involved in the viral process in the host-virus interaction, as metal (Zinc) ion binding. It seems to be upregulated after 7 hours of Marburg virus in humans and then after 23 hours downregulated. In bats, it seems to be upregulated with the time during Marburg virus infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	157	207	145	177	225	448	186	314	111
Read_Max	R. aegyptiacus	Transcriptome	371	328	283	265	232	206	199	267	401
Read_Max	R. aegyptiacus	Genome	455	379	272	338	225	182	205	444	524
DESeq	H. sapiens	Genome	5000.85	4798.48	3833.3	4928.75	3943.0	10059.91	4524.75	5167.2	3540.31
DESeq	R. aegyptiacus	Transcriptome	5191.39	4302.54	5466.16	4745.08	4274.04	3379.62	3762.04	3926.32	5248.38
DESeq	R. aegyptiacus	Genome	10593.7	8863.08	10598.77	9242.85	8612.09	7337.71	7866.1	7856.51	10852.23

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	5000.85	4928.75	4524.75	-0.02	-0.14	-0.12
7h	4798.48	3943.0	5167.2	-0.28	0.11	0.39
23h	3833.3	10059.91	3540.31	1.39	-0.11	-1.51

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	5000.85	4798.48	3833.3	-0.06	-0.38	-0.32
Ebov	4928.75	3943.0	10059.91	-0.32	1.03	1.35
Marv	4524.75	5167.2	3540.31	0.19	-0.35	-0.55

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	5191.39	4745.08	3762.04	-0.13	-0.46	-0.33
7h	4302.54	4274.04	3926.32	-0.01	-0.13	-0.12
23h	5466.16	3379.62	5248.38	-0.69	-0.06	0.64

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	5191.39	4302.54	5466.16	-0.27	0.07	0.35
Ebov	4745.08	4274.04	3379.62	-0.15	-0.49	-0.34
Marv	3762.04	3926.32	5248.38	0.06	0.48	0.42

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material