MCM2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MCM2 BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19,D3S3194, KIAA0030, BM28 minichromosome maintenance complex component 2 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The minichromosome maintenance complex component 2 (EC:3.6.4.12) gene is involved in DNA replication and cell cycle. This gene seems to be downregulated after 7 hours of viral infection (ebola and marburg) in humans, and also seems to be downregulated in bats infected with ebola after 3 hours.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome574 768 485 785 786 354 1162 1107 326
Read_Max
batR. aegyptiacusTranscriptome 763 623 284 463 430 510 430 538 472
Read_Max
bat_genomeR. aegyptiacusGenome 856 499 251 590 373 300 367 666 535
DESeq
humanH. sapiensGenome 9913.44 11595.94 8752.75 13960.68 10127.93 4938.34 13758.2 12133.54 5421.42
DESeq
batR. aegyptiacusTranscriptome 7694.17 8053.12 4403.42 6163.45 6214.54 6470.8 6784.45 5931.52 5049.82
DESeq
bat_genomeR. aegyptiacusGenome 8098.03 6445.38 4333.68 8910.06 6712.43 6871.68 7264.48 6190.53 5255.3

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 9913.44 13960.68 13758.2 0.49 0.47 -0.02
7h 11595.94 10127.93 12133.54 -0.2 0.07 0.26
23h 8752.75 4938.34 5421.42 -0.83 -0.69 0.13

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 9913.44 11595.94 8752.75 0.23 -0.18 -0.41
Ebov 13960.68 10127.93 4938.34 -0.46 -1.5 -1.04
Marv 13758.2 12133.54 5421.42 -0.18 -1.34 -1.16

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7694.17 6163.45 6784.45 -0.32 -0.18 0.14
7h 8053.12 6214.54 5931.52 -0.37 -0.44 -0.07
23h 4403.42 6470.8 5049.82 0.56 0.2 -0.36

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7694.17 8053.12 4403.42 0.07 -0.81 -0.87
Ebov 6163.45 6214.54 6470.8 0.01 0.07 0.06
Marv 6784.45 5931.52 5049.82 -0.19 -0.43 -0.23