UNC119B
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| UNC119B | POC7B,MGC5139, POC7B | unc-119 homolog B (C. elegans) | NM_001080533 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The unc-119 homolog B (C. elegans) gene is a Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells. It is involved in lipid binding, cilium morphogenesis and protein transport.
It did not present any particularly interesting differential expression pattern in the samples analyzed except for the slightly downregulation after 23 hours of Marburg virus infection in the humans samples.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 118 | 198 | 187 | 186 | 221 | 445 | 234 | 285 | 137 |
Read_Max |  | R. aegyptiacus | Transcriptome | 265 | 258 | 213 | 292 | 222 | 274 | 205 | 305 | 249 |
Read_Max |  | R. aegyptiacus | Genome | 312 | 311 | 189 | 256 | 205 | 168 | 187 | 392 | 277 |
DESeq | | H. sapiens | Genome | 2791.66 | 3365.56 | 3353.77 | 3263.35 | 3706.43 | 7070.13 | 3267.71 | 3239.17 | 2492.11 |
DESeq | | R. aegyptiacus | Transcriptome | 1096.54 | 1137.43 | 1369.12 | 1455.08 | 1333.72 | 1377.85 | 1236.88 | 1460.08 | 1133.75 |
DESeq | | R. aegyptiacus | Genome | 3510.61 | 4313.35 | 3645.25 | 3411.76 | 4458.95 | 4548.05 | 3870.64 | 4317.59 | 3584.87 |