TUBB

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
TUBB	CDCBM6, M40, OK/SW-cl.56, TUBB1, TUBB5,OK/SW-cl.56, MGC16435, Tubb5	tubulin, beta class I	NM_178014	pdf

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Description

The tubulin, beta class I gene is involved in Phagosome, Gap junction and Pathogenic Escherichia coli infection. This gene seems to be downregulated after 23 hours of ebola infection in humans. In bats, in the control and ebola infected samples there is a slight downregulation, but not in the marburg infected samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	3066	2616	2259	2576	3390	1368	3135	3362	2301
Read_Max	R. aegyptiacus	Transcriptome	4937	5072	2188	4211	3313	2563	3570	4575	4002
Read_Max	R. aegyptiacus	Genome	5271	4274	1845	4565	2795	1509	3053	5543	4228
DESeq	H. sapiens	Genome	38986.07	31390.65	22787.32	32905.15	26215.41	11902.2	33062.85	29847.95	23950.9
DESeq	R. aegyptiacus	Transcriptome	38302.16	42854.85	22579.88	34185.65	31764.08	22038.36	35116.32	32665.15	26879.05
DESeq	R. aegyptiacus	Genome	41583.31	34805.24	21902.72	48950.55	33305.43	23622.7	38189.11	32322.06	26501.7

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	38986.07	32905.15	33062.85	-0.24	-0.24	0.01
7h	31390.65	26215.41	29847.95	-0.26	-0.07	0.19
23h	22787.32	11902.2	23950.9	-0.94	0.07	1.01

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	38986.07	31390.65	22787.32	-0.31	-0.77	-0.46
Ebov	32905.15	26215.41	11902.2	-0.33	-1.47	-1.14
Marv	33062.85	29847.95	23950.9	-0.15	-0.47	-0.32

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	38302.16	34185.65	35116.32	-0.16	-0.13	0.04
7h	42854.85	31764.08	32665.15	-0.43	-0.39	0.04
23h	22579.88	22038.36	26879.05	-0.04	0.25	0.29

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	38302.16	42854.85	22579.88	0.16	-0.76	-0.92
Ebov	34185.65	31764.08	22038.36	-0.11	-0.63	-0.53
Marv	35116.32	32665.15	26879.05	-0.1	-0.39	-0.28

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material