TUBB

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TUBB CDCBM6, M40, OK/SW-cl.56, TUBB1, TUBB5,OK/SW-cl.56, MGC16435, Tubb5 tubulin, beta class I NM_178014 pdf

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Description

The tubulin, beta class I gene is involved in Phagosome, Gap junction and Pathogenic Escherichia coli infection. This gene seems to be downregulated after 23 hours of ebola infection in humans. In bats, in the control and ebola infected samples there is a slight downregulation, but not in the marburg infected samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome3066 2616 2259 2576 3390 1368 3135 3362 2301
Read_Max
batR. aegyptiacusTranscriptome 4937 5072 2188 4211 3313 2563 3570 4575 4002
Read_Max
bat_genomeR. aegyptiacusGenome 5271 4274 1845 4565 2795 1509 3053 5543 4228
DESeq
humanH. sapiensGenome 38986.07 31390.65 22787.32 32905.15 26215.41 11902.2 33062.85 29847.95 23950.9
DESeq
batR. aegyptiacusTranscriptome 38302.16 42854.85 22579.88 34185.65 31764.08 22038.36 35116.32 32665.15 26879.05
DESeq
bat_genomeR. aegyptiacusGenome 41583.31 34805.24 21902.72 48950.55 33305.43 23622.7 38189.11 32322.06 26501.7

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 38986.07 32905.15 33062.85 -0.24 -0.24 0.01
7h 31390.65 26215.41 29847.95 -0.26 -0.07 0.19
23h 22787.32 11902.2 23950.9 -0.94 0.07 1.01

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 38986.07 31390.65 22787.32 -0.31 -0.77 -0.46
Ebov 32905.15 26215.41 11902.2 -0.33 -1.47 -1.14
Marv 33062.85 29847.95 23950.9 -0.15 -0.47 -0.32

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 38302.16 34185.65 35116.32 -0.16 -0.13 0.04
7h 42854.85 31764.08 32665.15 -0.43 -0.39 0.04
23h 22579.88 22038.36 26879.05 -0.04 0.25 0.29

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 38302.16 42854.85 22579.88 0.16 -0.76 -0.92
Ebov 34185.65 31764.08 22038.36 -0.11 -0.63 -0.53
Marv 35116.32 32665.15 26879.05 -0.1 -0.39 -0.28