GPATCH4

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
GPATCH4	GPATC4,FLJ20249, DKFZP434F1735	G patch domain containing 4	NM_017725	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The G patch domain containing 4 gene is involved in nucleic acid binding and hematopoietic progenitor cell differentiation. During Marburg virus infection, after 23 hours this gene seems to be slightly downregulated in humans and slightly upregulated in bats.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	268	379	290	317	523	885	497	585	282
Read_Max	R. aegyptiacus	Transcriptome	38	42	32	36	27	38	24	43	37
Read_Max	R. aegyptiacus	Genome	47	26	27	34	23	22	21	39	40
DESeq	H. sapiens	Genome	3067.69	4131.49	3230.66	4319.63	4190.14	8880.84	4506.32	4734.75	3259.78
DESeq	R. aegyptiacus	Transcriptome	184.15	202.51	234.31	140.18	142.27	287.15	180.1	154.67	196.93
DESeq	R. aegyptiacus	Genome	210.55	141.47	266.67	209.35	151.79	300.24	202.42	153.04	210.62

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3067.69	4319.63	4506.32	0.49	0.55	0.06
7h	4131.49	4190.14	4734.75	0.02	0.2	0.18
23h	3230.66	8880.84	3259.78	1.46	0.01	-1.45

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3067.69	4131.49	3230.66	0.43	0.07	-0.35
Ebov	4319.63	4190.14	8880.84	-0.04	1.04	1.08
Marv	4506.32	4734.75	3259.78	0.07	-0.47	-0.54

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	184.15	140.18	180.1	-0.39	-0.03	0.36
7h	202.51	142.27	154.67	-0.51	-0.39	0.12
23h	234.31	287.15	196.93	0.29	-0.25	-0.54

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	184.15	202.51	234.31	0.14	0.35	0.21
Ebov	140.18	142.27	287.15	0.02	1.03	1.01
Marv	180.1	154.67	196.93	-0.22	0.13	0.35

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material