BCL2L13

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
BCL2L13	BCL-RAMBO, MIL1,MIL1, BCL-RAMBO	BCL2-like 13 (apoptosis facilitator)	NM_015367	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene.

A small variation can be seen in Marburg and Ebola 23 h, in different directions.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	216	274	218	205	282	510	284	317	217
Read_Max	R. aegyptiacus	Transcriptome	243	201	128	223	179	266	211	253	180
Read_Max	R. aegyptiacus	Genome	385	306	175	246	250	226	235	483	325
DESeq	H. sapiens	Genome	3422.86	4034.6	3705.23	3637.5	3969.83	7047.76	3639.65	3743.56	4057.89
DESeq	R. aegyptiacus	Transcriptome	2011.46	1846.33	1355.68	1828.67	1818.85	2229.89	1937.7	1845.1	1355.05
DESeq	R. aegyptiacus	Genome	5820.65	5381.19	4073.7	5022.34	5595.18	6943.48	6021.87	5228.69	4214.18

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3422.86	3637.5	3639.65	0.09	0.09	0.0
7h	4034.6	3969.83	3743.56	-0.02	-0.11	-0.08
23h	3705.23	7047.76	4057.89	0.93	0.13	-0.8

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3422.86	4034.6	3705.23	0.24	0.11	-0.12
Ebov	3637.5	3969.83	7047.76	0.13	0.95	0.83
Marv	3639.65	3743.56	4057.89	0.04	0.16	0.12

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2011.46	1828.67	1937.7	-0.14	-0.05	0.08
7h	1846.33	1818.85	1845.1	-0.02	-0.0	0.02
23h	1355.68	2229.89	1355.05	0.72	-0.0	-0.72

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2011.46	1846.33	1355.68	-0.12	-0.57	-0.45
Ebov	1828.67	1818.85	2229.89	-0.01	0.29	0.29
Marv	1937.7	1845.1	1355.05	-0.07	-0.52	-0.45

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material