TRIM22

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TRIM22 STAF50, GPSTAF50, RNF94 tripartite motif containing 22 NM_006074 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants.

Some of the exons have been not detected to be transcribed. We see a slight up-/downregulation.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome7 6 7 7 14 8 12 11 3
Read_Max
batR. aegyptiacusTranscriptome 57 60 59 69 68 73 55 81 85
Read_Max
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA
DESeq
humanH. sapiensGenome 26.37 21.4 23.83 23.81 30.27 8.9 27.32 27.38 31.45
DESeq
batR. aegyptiacusTranscriptome 341.26 346.83 390.67 401.15 440.13 333.34 341.4 387.67 446.23
DESeq
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 26.37 23.81 27.32 -0.15 0.05 0.2
7h 21.4 30.27 27.38 0.5 0.36 -0.14
23h 23.83 8.9 31.45 -1.42 0.4 1.82

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 26.37 21.4 23.83 -0.3 -0.15 0.16
Ebov 23.81 30.27 8.9 0.35 -1.42 -1.77
Marv 27.32 27.38 31.45 0.0 0.2 0.2

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 341.26 401.15 341.4 0.23 0.0 -0.23
7h 346.83 440.13 387.67 0.34 0.16 -0.18
23h 390.67 333.34 446.23 -0.23 0.19 0.42

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 341.26 346.83 390.67 0.02 0.2 0.17
Ebov 401.15 440.13 333.34 0.13 -0.27 -0.4
Marv 341.4 387.67 446.23 0.18 0.39 0.2