TRIM22
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| TRIM22 | STAF50, GPSTAF50, RNF94 | tripartite motif containing 22 | NM_006074 |  |
 |
 |
NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants.
Some of the exons have been not detected to be transcribed. We see a slight up-/downregulation.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 7 | 6 | 7 | 7 | 14 | 8 | 12 | 11 | 3 |
Read_Max |  | R. aegyptiacus | Transcriptome | 57 | 60 | 59 | 69 | 68 | 73 | 55 | 81 | 85 |
Read_Max |  | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | H. sapiens | Genome | 26.37 | 21.4 | 23.83 | 23.81 | 30.27 | 8.9 | 27.32 | 27.38 | 31.45 |
DESeq | | R. aegyptiacus | Transcriptome | 341.26 | 346.83 | 390.67 | 401.15 | 440.13 | 333.34 | 341.4 | 387.67 | 446.23 |
DESeq | | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |