IRAK1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
IRAK1	IRAK, pelle	interleukin-1 receptor-associated kinase 1		pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

No differential expression was found for this gene.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	230	303	181	227	329	279	336	431	219
Read_Max	R. aegyptiacus	Transcriptome	80	90	50	53	57	124	67	55	99
Read_Max	R. aegyptiacus	Genome	108	66	49	92	70	80	74	117	124
DESeq	H. sapiens	Genome	4449.83	4576.15	3265.41	4725.71	3917.8	4026.41	4794.05	5045.7	4274.27
DESeq	R. aegyptiacus	Transcriptome	647.07	677.23	512.82	469.82	549.64	930.02	666.22	471.94	633.41
DESeq	R. aegyptiacus	Genome	1734.25	1461.21	1423.73	1825.86	1469.95	2392.82	2056.77	1369.42	1820.26

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	4449.83	4725.71	4794.05	0.09	0.11	0.02
7h	4576.15	3917.8	5045.7	-0.22	0.14	0.37
23h	3265.41	4026.41	4274.27	0.3	0.39	0.09

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	4449.83	4576.15	3265.41	0.04	-0.45	-0.49
Ebov	4725.71	3917.8	4026.41	-0.27	-0.23	0.04
Marv	4794.05	5045.7	4274.27	0.07	-0.17	-0.24

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	647.07	469.82	666.22	-0.46	0.04	0.5
7h	677.23	549.64	471.94	-0.3	-0.52	-0.22
23h	512.82	930.02	633.41	0.86	0.3	-0.55

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	647.07	677.23	512.82	0.07	-0.34	-0.4
Ebov	469.82	549.64	930.02	0.23	0.99	0.76
Marv	666.22	471.94	633.41	-0.5	-0.07	0.42

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material