MX1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| MX1 | Interferon-Induced Protein P78,Mx1,IFI-78K, MxA | MX dynamin-like GTPase 1 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.
The gene is lowly expressed and shows a small ($\sim$10) number of reads mapping in the first intron in all conditions.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 8 | 9 | 10 | 13 | 22 | 8 | 14 | 22 | 6 |
Read_Max |  | R. aegyptiacus | Transcriptome | 109 | 128 | 150 | 123 | 98 | 159 | 61 | 140 | 268 |
Read_Max |  | R. aegyptiacus | Genome | 0 | 2 | 2 | 0 | 2 | 2 | 0 | 3 | 1 |
DESeq | | H. sapiens | Genome | 2.01 | 1.0 | 5.96 | 3.28 | 5.06 | 19.42 | 8.89 | 8.19 | 16.22 |
DESeq | | R. aegyptiacus | Transcriptome | 839.46 | 990.38 | 1833.31 | 1060.43 | 973.44 | 1474.09 | 691.8 | 1099.86 | 2237.63 |
DESeq | | R. aegyptiacus | Genome | 0.0 | 4.56 | 7.81 | 0.0 | 2.23 | 5.22 | 0.0 | 3.17 | 3.42 |