HERC6
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| HERC6 | FLJ20637 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.
The gene was only very slightly expressed in human cells and bat cells cells, no differences in expression were observed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 4 | 4 | 3 | 5 | 3 | 5 | 4 | 3 | 7 |
Read_Max |  | R. aegyptiacus | Transcriptome | 45 | 46 | 22 | 27 | 31 | 30 | 37 | 40 | 36 |
Read_Max |  | R. aegyptiacus | Genome | 55 | 30 | 21 | 51 | 29 | 19 | 33 | 58 | 53 |
DESeq | | H. sapiens | Genome | 18.25 | 17.32 | 20.86 | 37.5 | 19.7 | 22.05 | 22.93 | 21.78 | 44.49 |
DESeq | | R. aegyptiacus | Transcriptome | 512.65 | 466.64 | 308.83 | 334.3 | 381.0 | 307.68 | 494.91 | 384.36 | 413.86 |
DESeq | | R. aegyptiacus | Genome | 709.0 | 439.91 | 410.61 | 602.36 | 464.31 | 417.73 | 630.86 | 509.86 | 526.56 |