NMI

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
NMI N-myc (and STAT) interactor NM_004688 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.

This gene is generally low expressed. No differences between our RNA-Seq data observed.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome13 24 8 16 18 13 21 19 10
Read_Max
batR. aegyptiacusTranscriptome 244 179 141 186 144 139 163 184 182
Read_Max
bat_genomeR. aegyptiacusGenome 236 192 115 163 121 76 135 223 187
DESeq
humanH. sapiensGenome 83.2 72.39 54.61 85.41 70.1 28.63 85.21 73.74 68.42
DESeq
batR. aegyptiacusTranscriptome 840.3 738.04 851.19 877.29 990.96 868.43 1037.76 1002.36 918.57
DESeq
bat_genomeR. aegyptiacusGenome 1081.11 1141.77 1030.98 975.63 1263.46 1160.51 1340.44 1261.58 1163.56

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 83.2 85.41 85.21 0.04 0.03 -0.0
7h 72.39 70.1 73.74 -0.05 0.03 0.07
23h 54.61 28.63 68.42 -0.93 0.33 1.26

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 83.2 72.39 54.61 -0.2 -0.61 -0.41
Ebov 85.41 70.1 28.63 -0.28 -1.58 -1.29
Marv 85.21 73.74 68.42 -0.21 -0.32 -0.11

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 840.3 877.29 1037.76 0.06 0.3 0.24
7h 738.04 990.96 1002.36 0.43 0.44 0.02
23h 851.19 868.43 918.57 0.03 0.11 0.08

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 840.3 738.04 851.19 -0.19 0.02 0.21
Ebov 877.29 990.96 868.43 0.18 -0.01 -0.19
Marv 1037.76 1002.36 918.57 -0.05 -0.18 -0.13