NDUFA12
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| NDUFA12 | DAP13, B17.2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 | NM_018838 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.
This gene shows no differential expression during infection.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 118 | 125 | 94 | 118 | 156 | 174 | 144 | 201 | 91 |
Read_Max |  | R. aegyptiacus | Transcriptome | 122 | 127 | 122 | 128 | 79 | 119 | 101 | 158 | 189 |
Read_Max |  | R. aegyptiacus | Genome | 175 | 139 | 103 | 158 | 83 | 75 | 108 | 195 | 201 |
DESeq | | H. sapiens | Genome | 422.14 | 373.25 | 304.8 | 404.8 | 375.77 | 389.2 | 407.15 | 417.46 | 323.94 |
DESeq | | R. aegyptiacus | Transcriptome | 222.8 | 232.46 | 264.85 | 234.5 | 194.83 | 239.67 | 252.4 | 278.61 | 293.15 |
DESeq | | R. aegyptiacus | Genome | 500.17 | 433.53 | 457.47 | 462.14 | 381.72 | 454.28 | 435.19 | 418.68 | 448.64 |