RELA

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RELA NFKB3, p65,p65 v-rel avian reticuloendotheliosis viral oncogene homolog A NM_021975 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA.

The gene is 2-fold upregulated exclusively in the human cells Ebola 23 h sample.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome64 104 83 90 109 262 109 147 82
Read_Max
batR. aegyptiacusTranscriptome 206 217 170 156 142 195 146 169 243
Read_Max
bat_genomeR. aegyptiacusGenome 223 159 153 206 134 117 124 219 264
DESeq
humanH. sapiensGenome 682.94 1025.97 692.01 995.68 816.39 2315.71 1038.73 1196.03 863.27
DESeq
batR. aegyptiacusTranscriptome 1754.37 1751.93 1939.58 1384.57 1402.72 2081.04 1605.09 1353.5 1677.82
DESeq
bat_genomeR. aegyptiacusGenome 2088.32 1706.72 2346.48 2175.43 1840.5 2802.72 1991.55 1665.98 2049.72

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 682.94 995.68 1038.73 0.54 0.6 0.06
7h 1025.97 816.39 1196.03 -0.33 0.22 0.55
23h 692.01 2315.71 863.27 1.74 0.32 -1.42

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 682.94 1025.97 692.01 0.59 0.02 -0.57
Ebov 995.68 816.39 2315.71 -0.29 1.22 1.5
Marv 1038.73 1196.03 863.27 0.2 -0.27 -0.47

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1754.37 1384.57 1605.09 -0.34 -0.13 0.21
7h 1751.93 1402.72 1353.5 -0.32 -0.37 -0.05
23h 1939.58 2081.04 1677.82 0.1 -0.21 -0.31

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1754.37 1751.93 1939.58 -0.0 0.14 0.15
Ebov 1384.57 1402.72 2081.04 0.02 0.59 0.57
Marv 1605.09 1353.5 1677.82 -0.25 0.06 0.31