NRF1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
NRF1 EWG, ALPHA-PAL nuclear respiratory factor 1 NM_001040110 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens nuclear respiratory factor 1 (NRF1), transcript variant 1, mRNA. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants.

Some expression upstream of 5'-UTR in all samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome82 91 55 71 73 63 105 92 48
Read_Max
batR. aegyptiacusTranscriptome 166 135 56 93 98 98 96 101 87
Read_Max
bat_genomeR. aegyptiacusGenome 179 92 54 134 83 58 85 127 103
DESeq
humanH. sapiensGenome 1268.47 1002.52 970.99 1237.5 1030.2 985.31 1242.24 984.2 829.56
DESeq
batR. aegyptiacusTranscriptome 908.35 867.84 467.63 729.87 682.15 678.52 857.55 734.67 582.68
DESeq
bat_genomeR. aegyptiacusGenome 2072.85 1858.23 1747.31 1870.29 1774.65 1700.95 2035.4 1747.65 1574.54

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1268.47 1237.5 1242.24 -0.04 -0.03 0.01
7h 1002.52 1030.2 984.2 0.04 -0.03 -0.07
23h 970.99 985.31 829.56 0.02 -0.23 -0.25

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1268.47 1002.52 970.99 -0.34 -0.39 -0.05
Ebov 1237.5 1030.2 985.31 -0.26 -0.33 -0.06
Marv 1242.24 984.2 829.56 -0.34 -0.58 -0.25

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 908.35 729.87 857.55 -0.32 -0.08 0.23
7h 867.84 682.15 734.67 -0.35 -0.24 0.11
23h 467.63 678.52 582.68 0.54 0.32 -0.22

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 908.35 867.84 467.63 -0.07 -0.96 -0.89
Ebov 729.87 682.15 678.52 -0.1 -0.11 -0.01
Marv 857.55 734.67 582.68 -0.22 -0.56 -0.33