OAS2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |  |
NONE | NONE | NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.
No expression was found in human cells or in a reliable BLAST hit.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Read_Max |  | R. aegyptiacus | Transcriptome | 1 | 2 | 3 | 1 | 2 | 4 | 2 | 4 | 5 |
Read_Max |  | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | H. sapiens | Genome | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
DESeq | | R. aegyptiacus | Transcriptome | 2.68 | 4.63 | 14.44 | 2.83 | 5.38 | 16.4 | 6.56 | 7.61 | 19.37 |
DESeq | | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |