RCHY1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RCHY1 ZCHY, ARNIP, CHIMP, PIRH2, RNF199, ZNF363, PRO1996,CHIMP, DKFZp586C1620, ZCHY ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase NM_015436 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

The exon annotation of the gene displays not the expression from the RNA-Seq data. The first exons are not used.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome143 112 88 139 171 268 185 177 86
Read_Max
batR. aegyptiacusTranscriptome 79 90 104 89 78 104 65 103 115
Read_Max
bat_genomeR. aegyptiacusGenome 87 93 83 88 68 67 60 131 132
DESeq
humanH. sapiensGenome 1131.47 833.22 808.17 1016.21 996.05 1212.96 1089.61 924.25 839.34
DESeq
batR. aegyptiacusTranscriptome 295.89 324.14 440.75 392.91 376.62 414.18 336.95 442.2 369.25
DESeq
bat_genomeR. aegyptiacusGenome 669.46 796.77 861.38 612.24 789.11 789.77 741.07 915.06 791.98

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1131.47 1016.21 1089.61 -0.15 -0.05 0.1
7h 833.22 996.05 924.25 0.26 0.15 -0.11
23h 808.17 1212.96 839.34 0.59 0.05 -0.53

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1131.47 833.22 808.17 -0.44 -0.49 -0.04
Ebov 1016.21 996.05 1212.96 -0.03 0.26 0.28
Marv 1089.61 924.25 839.34 -0.24 -0.38 -0.14

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 295.89 392.91 336.95 0.41 0.19 -0.22
7h 324.14 376.62 442.2 0.22 0.45 0.23
23h 440.75 414.18 369.25 -0.09 -0.26 -0.17

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 295.89 324.14 440.75 0.13 0.57 0.44
Ebov 392.91 376.62 414.18 -0.06 0.08 0.14
Marv 336.95 442.2 369.25 0.39 0.13 -0.26