MIP

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MIP CTRCT15, AQP0, LIM1, MIP26,MP26 major intrinsic protein of lens fiber NM_012064 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13.

This gene shows week uniform expression in all probes.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome2 0 1 0 1 0 2 0 1
Read_Max
batR. aegyptiacusTranscriptome 1 NA NA NA NA NA 2 3 2
Read_Max
bat_genomeR. aegyptiacusGenome 7 2 3 1 3 2 4 6 2
DESeq
humanH. sapiensGenome 5.06 1.0 2.99 1.0 2.63 1.0 3.63 1.0 3.17
DESeq
batR. aegyptiacusTranscriptome 1.84 1.0 1.0 1.0 1.0 1.0 5.45 4.3 2.75
DESeq
bat_genomeR. aegyptiacusGenome 12.03 5.48 8.93 1.97 13.39 7.83 15.74 14.27 5.14

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 5.06 1.0 3.63 -2.34 -0.48 1.86
7h 1.0 2.63 1.0 1.4 0.0 -1.4
23h 2.99 1.0 3.17 -1.58 0.08 1.66

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 5.06 1.0 2.99 -2.34 -0.76 1.58
Ebov 1.0 2.63 1.0 1.4 0.0 -1.4
Marv 3.63 1.0 3.17 -1.86 -0.2 1.66

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.84 1.0 5.45 -0.88 1.57 2.45
7h 1.0 1.0 4.3 0.0 2.1 2.1
23h 1.0 1.0 2.75 0.0 1.46 1.46

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.84 1.0 1.0 -0.88 -0.88 0.0
Ebov 1.0 1.0 1.0 0.0 0.0 0.0
Marv 5.45 4.3 2.75 -0.34 -0.99 -0.64