IFIT5

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
IFIT5	RI58	interferon-induced protein with tetratricopeptide repeats 5	NM_012420	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens interferon-induced protein with tetratricopeptide repeats 5 (IFIT5), mRNA.

This gene is downregulated more than 2-fold exclusively in human cells Ebola virus infected cells. A bat cells homologue was found but did not show significant expression changes.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	59	45	39	38	41	15	50	55	36
Read_Max	R. aegyptiacus	Transcriptome	504	410	378	547	402	456	467	557	580
Read_Max	R. aegyptiacus	Genome	545	542	323	386	334	271	394	666	632
DESeq	H. sapiens	Genome	577.4	382.43	434.86	466.4	359.51	64.16	452.76	371.9	322.85
DESeq	R. aegyptiacus	Transcriptome	3547.23	3105.3	3253.95	3679.24	3706.78	3266.7	4041.26	3629.71	3213.81
DESeq	R. aegyptiacus	Genome	3400.61	3399.75	2801.72	3205.37	3420.95	3139.51	3899.88	3318.48	2978.69

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	577.4	466.4	452.76	-0.31	-0.35	-0.04
7h	382.43	359.51	371.9	-0.09	-0.04	0.05
23h	434.86	64.16	322.85	-2.76	-0.43	2.33

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	577.4	382.43	434.86	-0.59	-0.41	0.19
Ebov	466.4	359.51	64.16	-0.38	-2.86	-2.49
Marv	452.76	371.9	322.85	-0.28	-0.49	-0.2

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3547.23	3679.24	4041.26	0.05	0.19	0.14
7h	3105.3	3706.78	3629.71	0.26	0.23	-0.03
23h	3253.95	3266.7	3213.81	0.01	-0.02	-0.02

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3547.23	3105.3	3253.95	-0.19	-0.12	0.07
Ebov	3679.24	3706.78	3266.7	0.01	-0.17	-0.18
Marv	4041.26	3629.71	3213.81	-0.15	-0.33	-0.18

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material