IFI35

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
IFI35 IFP35, interferon-induced protein 35 interferon-induced protein 35 NM_005533 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The cDNA encodes a 282-amino acid predicted protein containing a leucine zipper motif at the amino terminus. Unlike most other leucine zipper proteins, IFP35 lacks a basic domain associated with DNA binding. Western blots indicated that the IFP35 gene product can form homodimers and that there was increased nuclear localization following interferon treatment (omim.org).

The gene is slightly expressed in human cells and was not found to be expressed in bat cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome10 9 8 5 12 8 7 16 12
Read_Max
batR. aegyptiacusTranscriptome 16 9 8 10 11 7 10 13 15
Read_Max
bat_genomeR. aegyptiacusGenome 29 25 15 27 16 16 14 42 25
DESeq
humanH. sapiensGenome 36.52 36.7 30.78 16.97 30.27 22.05 22.93 51.36 54.28
DESeq
batR. aegyptiacusTranscriptome 47.21 24.6 35.2 32.13 29.47 30.51 28.81 38.18 45.61
DESeq
bat_genomeR. aegyptiacusGenome 305.94 334.04 272.25 293.28 214.3 237.58 265.39 352.86 238.88

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 36.52 16.97 22.93 -1.11 -0.67 0.43
7h 36.7 30.27 51.36 -0.28 0.48 0.76
23h 30.78 22.05 54.28 -0.48 0.82 1.3

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 36.52 36.7 30.78 0.01 -0.25 -0.25
Ebov 16.97 30.27 22.05 0.83 0.38 -0.46
Marv 22.93 51.36 54.28 1.16 1.24 0.08

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 47.21 32.13 28.81 -0.56 -0.71 -0.16
7h 24.6 29.47 38.18 0.26 0.63 0.37
23h 35.2 30.51 45.61 -0.21 0.37 0.58

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 47.21 24.6 35.2 -0.94 -0.42 0.52
Ebov 32.13 29.47 30.51 -0.12 -0.07 0.05
Marv 28.81 38.18 45.61 0.41 0.66 0.26