MAPK3
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| MAPK3 | ERK-1, ERT2,ERK1, p44mapk, p44erk1 | mitogen-activated protein kinase 3 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.
Gene slightly enriched in Ebola infected cells after 7 h and 23 h in human cells, and Ebola and Marbug infected cells in bat cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 76 | 70 | 58 | 55 | 84 | 91 | 63 | 90 | 61 |
Read_Max |  | R. aegyptiacus | Transcriptome | 22 | 31 | 35 | 31 | 19 | 37 | 20 | 23 | 42 |
Read_Max |  | R. aegyptiacus | Genome | 59 | 70 | 65 | 59 | 38 | 56 | 45 | 103 | 139 |
DESeq | | H. sapiens | Genome | 482.01 | 507.88 | 492.45 | 442.44 | 428.61 | 477.36 | 383.46 | 414.26 | 421.8 |
DESeq | | R. aegyptiacus | Transcriptome | 118.62 | 136.25 | 190.34 | 100.81 | 128.03 | 152.42 | 100.0 | 124.93 | 203.06 |
DESeq | | R. aegyptiacus | Genome | 381.57 | 419.84 | 618.14 | 505.59 | 377.25 | 563.94 | 417.2 | 413.92 | 702.93 |