IRF7

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
IRF7		interferon regulatory factor 7	NM_001572	pdf		NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.

Gene seems to be not expressed in human cells cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	6	9	4	4	3	8	6	3	4
Read_Max	R. aegyptiacus	Transcriptome	2	2	2	NA	NA	NA	NA	NA	3
Read_Max	R. aegyptiacus	Genome	3	3	3	2	4	2	0	3	4
DESeq	H. sapiens	Genome	43.62	34.66	20.86	32.94	10.76	40.48	23.81	8.19	18.4
DESeq	R. aegyptiacus	Transcriptome	3.52	2.82	5.89	1.0	1.0	1.0	1.0	1.0	3.62
DESeq	R. aegyptiacus	Genome	12.89	5.48	16.74	5.92	12.28	6.53	0.0	3.17	11.13

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	43.62	32.94	23.81	-0.41	-0.87	-0.47
7h	34.66	10.76	8.19	-1.69	-2.08	-0.39
23h	20.86	40.48	18.4	0.96	-0.18	-1.14

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	43.62	34.66	20.86	-0.33	-1.06	-0.73
Ebov	32.94	10.76	40.48	-1.61	0.3	1.91
Marv	23.81	8.19	18.4	-1.54	-0.37	1.17

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3.52	1.0	1.0	-1.82	-1.82	0.0
7h	2.82	1.0	1.0	-1.5	-1.5	0.0
23h	5.89	1.0	3.62	-2.56	-0.7	1.86

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3.52	2.82	5.89	-0.32	0.74	1.06
Ebov	1.0	1.0	1.0	0.0	0.0	0.0
Marv	1.0	1.0	3.62	0.0	1.86	1.86

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material