MAPK12

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MAPK12 p38gamma,ERK6, PRKM12, p38gamma, SAPK-3 mitogen-activated protein kinase 12 NM_002969 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene.

The gene has a slightly higher expression in Marburg infected cells in bat cells after 23 h.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome70 71 70 58 77 128 81 92 81
Read_Max
batR. aegyptiacusTranscriptome 17 12 12 6 8 11 8 8 22
Read_Max
bat_genomeR. aegyptiacusGenome 15 10 12 12 11 12 8 15 23
DESeq
humanH. sapiensGenome 704.25 788.34 887.59 834.84 726.15 1423.51 820.31 925.05 1079.65
DESeq
batR. aegyptiacusTranscriptome 38.81 29.14 53.53 22.06 31.66 45.91 31.03 22.48 73.6
DESeq
bat_genomeR. aegyptiacusGenome 118.6 149.68 193.03 102.7 167.42 257.17 92.21 143.52 324.5

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 704.25 834.84 820.31 0.25 0.22 -0.03
7h 788.34 726.15 925.05 -0.12 0.23 0.35
23h 887.59 1423.51 1079.65 0.68 0.28 -0.4

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 704.25 788.34 887.59 0.16 0.33 0.17
Ebov 834.84 726.15 1423.51 -0.2 0.77 0.97
Marv 820.31 925.05 1079.65 0.17 0.4 0.22

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 38.81 22.06 31.03 -0.81 -0.32 0.49
7h 29.14 31.66 22.48 0.12 -0.37 -0.49
23h 53.53 45.91 73.6 -0.22 0.46 0.68

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 38.81 29.14 53.53 -0.41 0.46 0.88
Ebov 22.06 31.66 45.91 0.52 1.06 0.54
Marv 31.03 22.48 73.6 -0.47 1.25 1.71