GAS2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
GAS2 growth arrest-specific 2 NM_177553 pdf NONE

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Description

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.

The gene GAS2 is expressed in all human cells and bat cells datasets without significant changes in expression levels.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome194 213 186 170 220 221 248 239 212
Read_Max
batR. aegyptiacusTranscriptome 88 58 98 83 70 53 67 88 102
Read_Max
bat_genomeR. aegyptiacusGenome 100 92 91 58 53 34 65 117 120
DESeq
humanH. sapiensGenome 1859.07 1884.71 2199.11 1798.72 1987.04 1551.16 1709.79 1926.64 2276.82
DESeq
batR. aegyptiacusTranscriptome 326.97 312.34 674.07 430.45 445.61 279.45 401.47 471.94 652.66
DESeq
bat_genomeR. aegyptiacusGenome 478.68 706.42 1039.9 523.37 740.0 498.67 639.86 758.06 994.04

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1859.07 1798.72 1709.79 -0.05 -0.12 -0.07
7h 1884.71 1987.04 1926.64 0.08 0.03 -0.04
23h 2199.11 1551.16 2276.82 -0.5 0.05 0.55

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1859.07 1884.71 2199.11 0.02 0.24 0.22
Ebov 1798.72 1987.04 1551.16 0.14 -0.21 -0.36
Marv 1709.79 1926.64 2276.82 0.17 0.41 0.24

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 326.97 430.45 401.47 0.4 0.3 -0.1
7h 312.34 445.61 471.94 0.51 0.6 0.08
23h 674.07 279.45 652.66 -1.27 -0.05 1.22

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 326.97 312.34 674.07 -0.07 1.04 1.11
Ebov 430.45 445.61 279.45 0.05 -0.62 -0.67
Marv 401.47 471.94 652.66 0.23 0.7 0.47