RUVBL2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| RUVBL2 | RVB2, TIP48, TIP49b, Reptin52, ECP51, TIH2, INO80J, Rvb2 | RuvB-like AAA ATPase 2 |  |
 |
 |
 |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
The gene is relatively highly but uniformly expressed in bat cells and human cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 133 | 147 | 134 | 117 | 164 | 211 | 143 | 215 | 147 |
Read_Max |  | R. aegyptiacus | Transcriptome | 198 | 241 | 135 | 142 | 141 | 151 | 144 | 186 | 156 |
Read_Max |  | R. aegyptiacus | Genome | 214 | 150 | 110 | 184 | 117 | 87 | 117 | 193 | 144 |
DESeq | | H. sapiens | Genome | 1087.84 | 1164.67 | 889.58 | 1104.04 | 1039.95 | 1414.3 | 1112.42 | 1317.53 | 1052.46 |
DESeq | | R. aegyptiacus | Transcriptome | 1263.73 | 1682.95 | 1369.12 | 1203.27 | 1249.4 | 1086.57 | 1249.12 | 1203.13 | 1106.63 |
DESeq | | R. aegyptiacus | Genome | 1298.54 | 1235.78 | 1228.47 | 1725.13 | 1255.65 | 1146.15 | 1330.32 | 1214.0 | 1086.51 |