SP110
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| SP110 | SP110 nuclear body protein | NM_080424 |  |
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Description
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
The gene is slightly expressed in human cells regardless of the infectious state. In contrast, the gene could not be detected in the transcriptome of bat cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 9 | 15 | 11 | 7 | 12 | 8 | 15 | 17 | 10 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Read_Max |  | R. aegyptiacus | Genome | 17 | 25 | 30 | 19 | 13 | 18 | 11 | 21 | 37 |
DESeq | | H. sapiens | Genome | 86.24 | 98.91 | 101.28 | 85.41 | 94.49 | 37.85 | 99.25 | 132.89 | 91.25 |
DESeq | | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | R. aegyptiacus | Genome | 101.41 | 154.24 | 273.37 | 131.34 | 128.36 | 198.42 | 110.2 | 145.9 | 263.71 |