PIK3CA

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
PIK3CA PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. T

he gene is moderately expressed in both human cells and bat cells with a slightly higher expression in bat cells (regarding the read counts).

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome93 87 93 98 111 125 96 135 107
Read_Max
batR. aegyptiacusTranscriptome 255 172 130 183 136 176 140 232 153
Read_Max
bat_genomeR. aegyptiacusGenome 282 193 110 172 121 107 123 290 171
DESeq
humanH. sapiensGenome 1613.5 1358.45 1612.35 1543.2 1589.51 2157.8 1525.58 1441.43 1961.49
DESeq
batR. aegyptiacusTranscriptome 2709.61 1940.73 2224.2 2874.37 2575.56 2818.87 2796.48 2642.39 2047.82
DESeq
bat_genomeR. aegyptiacusGenome 4483.44 4429.26 3522.51 3457.18 4056.03 4785.63 4655.56 4068.61 3467.58

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1613.5 1543.2 1525.58 -0.06 -0.08 -0.02
7h 1358.45 1589.51 1441.43 0.23 0.09 -0.14
23h 1612.35 2157.8 1961.49 0.42 0.28 -0.14

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1613.5 1358.45 1612.35 -0.25 -0.0 0.25
Ebov 1543.2 1589.51 2157.8 0.04 0.48 0.44
Marv 1525.58 1441.43 1961.49 -0.08 0.36 0.44

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2709.61 2874.37 2796.48 0.09 0.05 -0.04
7h 1940.73 2575.56 2642.39 0.41 0.45 0.04
23h 2224.2 2818.87 2047.82 0.34 -0.12 -0.46

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2709.61 1940.73 2224.2 -0.48 -0.28 0.2
Ebov 2874.37 2575.56 2818.87 -0.16 -0.03 0.13
Marv 2796.48 2642.39 2047.82 -0.08 -0.45 -0.37