MX2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| MX2 | Myxovirus (Influenza Virus) Resistance 2 (Mouse), Interferon-Induced GTP-Binding Protein Mx2, GTP-Binding Protein MxB,MXB | MX dynamin-like GTPase 2 | NM_002463 |  |
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NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.
The gene MX2 is expressed throughout all datasets, but shows no significant changes.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 198 | 241 | 216 | 187 | 274 | 151 | 232 | 343 | 204 |
Read_Max |  | R. aegyptiacus | Transcriptome | 104 | 124 | 134 | 120 | 105 | 156 | 58 | 140 | 256 |
Read_Max |  | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | H. sapiens | Genome | 3517.24 | 3707.22 | 4103.35 | 3289.59 | 3605.62 | 2470.99 | 3565.96 | 3985.76 | 3931.76 |
DESeq | | R. aegyptiacus | Transcriptome | 296.73 | 367.71 | 614.21 | 388.33 | 342.67 | 538.65 | 220.14 | 409.15 | 768.99 |
DESeq | | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |