SP100

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SP100 F8WFE2 SP100 nuclear antigen NM_003113 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens SP100 nuclear antigen (SP100), transcript variant 5, mRNA. This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.

Low expression in human cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome11 23 26 21 32 44 28 30 34
Read_Max
batR. aegyptiacusTranscriptome 62 55 84 53 51 93 47 76 115
Read_Max
bat_genomeR. aegyptiacusGenome 76 77 74 68 57 59 47 101 131
DESeq
humanH. sapiensGenome 222.22 300.84 334.59 250.81 324.55 677.38 228.2 286.37 450.07
DESeq
batR. aegyptiacusTranscriptome 505.92 506.58 818.21 581.53 554.02 787.59 539.4 602.48 786.49
DESeq
bat_genomeR. aegyptiacusGenome 828.45 984.79 1215.08 836.4 865.0 1181.4 844.52 957.09 1149.01

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 222.22 250.81 228.2 0.17 0.04 -0.14
7h 300.84 324.55 286.37 0.11 -0.07 -0.18
23h 334.59 677.38 450.07 1.02 0.43 -0.59

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 222.22 300.84 334.59 0.44 0.59 0.15
Ebov 250.81 324.55 677.38 0.37 1.43 1.06
Marv 228.2 286.37 450.07 0.33 0.98 0.65

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 505.92 581.53 539.4 0.2 0.09 -0.11
7h 506.58 554.02 602.48 0.13 0.25 0.12
23h 818.21 787.59 786.49 -0.06 -0.06 -0.0

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 505.92 506.58 818.21 0.0 0.69 0.69
Ebov 581.53 554.02 787.59 -0.07 0.44 0.51
Marv 539.4 602.48 786.49 0.16 0.54 0.38