SP100
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| SP100 | F8WFE2 | SP100 nuclear antigen | NM_003113 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Homo sapiens SP100 nuclear antigen (SP100), transcript variant 5, mRNA. This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
Low expression in human cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 11 | 23 | 26 | 21 | 32 | 44 | 28 | 30 | 34 |
Read_Max |  | R. aegyptiacus | Transcriptome | 62 | 55 | 84 | 53 | 51 | 93 | 47 | 76 | 115 |
Read_Max |  | R. aegyptiacus | Genome | 76 | 77 | 74 | 68 | 57 | 59 | 47 | 101 | 131 |
DESeq | | H. sapiens | Genome | 222.22 | 300.84 | 334.59 | 250.81 | 324.55 | 677.38 | 228.2 | 286.37 | 450.07 |
DESeq | | R. aegyptiacus | Transcriptome | 505.92 | 506.58 | 818.21 | 581.53 | 554.02 | 787.59 | 539.4 | 602.48 | 786.49 |
DESeq | | R. aegyptiacus | Genome | 828.45 | 984.79 | 1215.08 | 836.4 | 865.0 | 1181.4 | 844.52 | 957.09 | 1149.01 |