PRAF2

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
PRAF2	JM4	PRA1 domain family, member 2	NM_007213	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis (UniProt).

This gene is 2-fold upregulated in human cells in Ebola infected cells and less upregulated in bat cells.

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source		Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max		H. sapiens	Genome	9	7	8	7	12	19	14	18	10
Read_Max		R. aegyptiacus	Transcriptome	139	176	155	144	101	134	133	157	234
Read_Max		R. aegyptiacus	Genome	159	152	117	166	82	80	120	202	276
DESeq		H. sapiens	Genome	44.64	58.11	53.62	43.21	62.78	106.27	58.02	60.95	56.45
DESeq		R. aegyptiacus	Transcriptome	485.76	567.4	713.16	553.15	460.94	520.69	488.23	442.2	801.36
DESeq		R. aegyptiacus	Genome	800.09	884.39	1027.63	962.8	694.24	886.37	800.67	746.96	1194.39

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	44.64	43.21	58.02	-0.05	0.38	0.43
7h	58.11	62.78	60.95	0.11	0.07	-0.04
23h	53.62	106.27	56.45	0.99	0.07	-0.91

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	44.64	58.11	53.62	0.38	0.26	-0.12
Ebov	43.21	62.78	106.27	0.54	1.3	0.76
Marv	58.02	60.95	56.45	0.07	-0.04	-0.11

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	485.76	553.15	488.23	0.19	0.01	-0.18
7h	567.4	460.94	442.2	-0.3	-0.36	-0.06
23h	713.16	520.69	801.36	-0.45	0.17	0.62

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	485.76	567.4	713.16	0.22	0.55	0.33
Ebov	553.15	460.94	520.69	-0.26	-0.09	0.18
Marv	488.23	442.2	801.36	-0.14	0.71	0.86