ELAVL1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| ELAVL1 | HuR, ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R), Hu Antigen R, Hua, MelG | ELAV like RNA binding protein 1 | NM_001419 |  |
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NONE |  |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The gene ELAVL1 codes for one of the best known RNA binding proteins HuR. HuR plays a major role in mRNA stability control and is mostly known as stabilizing element. The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Equally well expressed gene throughout datasets.
\igvfigure{ \beginfigure[H] \centering \caption\igv part one of gene ELAVL1. Equally well expressed gene throughout datasets. % <- say something about the figure here \endfigure }
\sashimifigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00277/snapshots//hg19.goi.00277_sashimi.eps % \caption\sashimi of gene ELAVL1. No extraordinary exon patterns. % <- say something about the figure here \endfigure }
\ucscfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00277/snapshots//hg19.goi.00277_ucsc.eps % \caption\ucsc of gene ELAVL1. Equally well expressed gene throughout datasets. % <- say something about the figure here \endfigure }
\setcounterfigure0 \enddocument
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 414 | 379 | 355 | 297 | 468 | 291 | 417 | 502 | 360 |
Read_Max |  | R. aegyptiacus | Transcriptome | 640 | 619 | 381 | 561 | 473 | 421 | 476 | 671 | 456 |
Read_Max |  | R. aegyptiacus | Genome | 730 | 585 | 325 | 607 | 396 | 244 | 405 | 805 | 493 |
DESeq | | H. sapiens | Genome | 4856.76 | 4118.23 | 4029.88 | 4134.84 | 4012.1 | 2676.27 | 4275.62 | 4008.94 | 3966.55 |
DESeq | | R. aegyptiacus | Transcriptome | 3417.85 | 3334.04 | 2485.61 | 3087.72 | 2915.03 | 2439.05 | 3160.23 | 3104.24 | 2290.99 |
DESeq | | R. aegyptiacus | Genome | 5405.56 | 4779.73 | 3747.9 | 5377.84 | 4689.99 | 3977.58 | 5166.1 | 4771.16 | 3756.11 |