PARD6B

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
PARD6B PAR-6B par-6 family cell polarity regulator beta NM_032521 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens par-6 partitioning defective 6 homolog beta (C. elegans) (PARD6B) gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.

This gene is upregulated in all samples, especially during HG19 ebola infection after 7h and RAE until 7h.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome172 94 107 116 136 336 121 106 145
Read_Max
batR. aegyptiacusTranscriptome 329 278 290 385 294 400 217 409 438
Read_Max
bat_genomeR. aegyptiacusGenome 328 383 229 258 228 231 181 451 482
DESeq
humanH. sapiensGenome 2680.04 1605.26 1762.27 1725.71 1578.12 3901.39 1894.01 1368.69 2277.9
DESeq
batR. aegyptiacusTranscriptome 1509.05 1573.12 1979.89 2130.84 2199.94 2326.13 1705.21 2087.18 2279.62
DESeq
bat_genomeR. aegyptiacusGenome 2465.59 3608.76 3110.79 2691.88 3651.99 4139.45 2918.16 3511.16 3860.57

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2680.04 1725.71 1894.01 -0.64 -0.5 0.13
7h 1605.26 1578.12 1368.69 -0.02 -0.23 -0.21
23h 1762.27 3901.39 2277.9 1.15 0.37 -0.78

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2680.04 1605.26 1762.27 -0.74 -0.6 0.13
Ebov 1725.71 1578.12 3901.39 -0.13 1.18 1.31
Marv 1894.01 1368.69 2277.9 -0.47 0.27 0.73

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1509.05 2130.84 1705.21 0.5 0.18 -0.32
7h 1573.12 2199.94 2087.18 0.48 0.41 -0.08
23h 1979.89 2326.13 2279.62 0.23 0.2 -0.03

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1509.05 1573.12 1979.89 0.06 0.39 0.33
Ebov 2130.84 2199.94 2326.13 0.05 0.13 0.08
Marv 1705.21 2087.18 2279.62 0.29 0.42 0.13