RRAS2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RRAS2 TC21, Ras related RAS viral (r-ras) oncogene homolog 2 NM_012250 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.

This gene is not regulated in the control samples of both organisms. After 23 h the expression level increases in Ebola infected human cells samples and in Marburg infected bat cells samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome95 68 65 108 95 145 94 82 79
Read_Max
batR. aegyptiacusTranscriptome 1359 1141 912 1174 1113 1371 1065 1553 1614
Read_Max
bat_genomeR. aegyptiacusGenome 1473 1239 802 1050 943 820 919 1893 1859
DESeq
humanH. sapiensGenome 612.92 508.9 493.44 629.52 474.95 808.98 629.08 519.78 609.91
DESeq
batR. aegyptiacusTranscriptome 4504.15 4385.14 3974.66 4311.05 4725.22 5118.33 4797.7 4770.7 4915.11
DESeq
bat_genomeR. aegyptiacusGenome 8041.31 7502.27 6819.63 8222.78 8266.09 8976.0 8592.55 8051.57 8498.56

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 612.92 629.52 629.08 0.04 0.04 -0.0
7h 508.9 474.95 519.78 -0.1 0.03 0.13
23h 493.44 808.98 609.91 0.71 0.31 -0.41

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 612.92 508.9 493.44 -0.27 -0.31 -0.04
Ebov 629.52 474.95 808.98 -0.41 0.36 0.77
Marv 629.08 519.78 609.91 -0.28 -0.04 0.23

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4504.15 4311.05 4797.7 -0.06 0.09 0.15
7h 4385.14 4725.22 4770.7 0.11 0.12 0.01
23h 3974.66 5118.33 4915.11 0.36 0.31 -0.06

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4504.15 4385.14 3974.66 -0.04 -0.18 -0.14
Ebov 4311.05 4725.22 5118.33 0.13 0.25 0.12
Marv 4797.7 4770.7 4915.11 -0.01 0.03 0.04