MAP3K14

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MAP3K14 FTDCR1B, HS, HSNIK, NIK,NIK, FTDCR1B mitogen-activated protein kinase kinase kinase 14 NM_003954 pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Expression levels are not available in human cells. %%%%%%%%%%%%%%%%%%%%%

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome6 6 6 9 9 16 12 12 7
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 123 153 87 124 96 70 61 163 190
DESeq
humanH. sapiensGenome 89.29 111.15 82.41 126.48 140.83 236.55 151.0 140.89 151.05
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 1536.59 1761.48 1838.8 1806.11 1818.18 1518.19 1404.54 1619.99 2015.48

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 89.29 126.48 151.0 0.5 0.76 0.26
7h 111.15 140.83 140.89 0.34 0.34 0.0
23h 82.41 236.55 151.05 1.52 0.87 -0.65

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 89.29 111.15 82.41 0.32 -0.12 -0.43
Ebov 126.48 140.83 236.55 0.16 0.9 0.75
Marv 151.0 140.89 151.05 -0.1 0.0 0.1

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA