ADAMTS2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ADAMTS2 NPI, PNPI, PCINP, PCPNI, PCI-NP, PC I-NP, ADAM-TS2, ADAMTS-2, ADAMTS-3,ADAMTS-3, hPCPNI, NPI ADAM metallopeptidase with thrombospondin type 1 motif, 2 NM_014244 pdf NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.

No expression in human cells and in the bat cells homolog. Something is expressed slightly directly 5' to the human cells gene (not annotated as a gene). No gene-expression plot was done for the gene, because there is nothing to see and it covers about 240kb.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome5 1 6 1 5 11 4 5 4
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA 2 2 NA NA 1
Read_Max
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA
DESeq
humanH. sapiensGenome 1.0 1.0 1.99 1.0 1.0 2.32 1.88 1.0 1.0
DESeq
batR. aegyptiacusTranscriptome 1.0 1.0 1.0 1.0 5.38 3.57 1.0 1.0 1.87
DESeq
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 1.0 1.88 0.0 0.91 0.91
7h 1.0 1.0 1.0 0.0 0.0 0.0
23h 1.99 2.32 1.0 0.22 -0.99 -1.21

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 1.99 0.0 0.99 0.99
Ebov 1.0 1.0 2.32 0.0 1.21 1.21
Marv 1.88 1.0 1.0 -0.91 -0.91 0.0

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 1.0 1.0 0.0 0.0 0.0
7h 1.0 5.38 1.0 2.43 0.0 -2.43
23h 1.0 3.57 1.87 1.84 0.9 -0.93

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 1.0 0.0 0.0 0.0
Ebov 1.0 5.38 3.57 2.43 1.84 -0.59
Marv 1.0 1.0 1.87 0.0 0.9 0.9