RAB11A

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RAB11A YL8 RAB11A, member RAS oncogene family pdf

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Description

The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene.

RAB11A is highly expressed in human cells and the homolog in bat cells is as well, although expression is a bit higher in human cells in comparison to bat cells. No significant variances were observed after virus infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome534 557 475 562 620 717 710 675 584
Read_Max
batR. aegyptiacusTranscriptome 357 329 222 296 235 287 240 372 372
Read_Max
bat_genomeR. aegyptiacusGenome 396 304 186 308 205 169 211 451 417
DESeq
humanH. sapiensGenome 4272.24 3704.16 4006.05 4418.87 3721.06 3127.63 4253.69 3575.7 4170.98
DESeq
batR. aegyptiacusTranscriptome 1251.13 1269.95 1162.68 1417.54 1266.92 1217.46 1339.22 1433.65 1383.91
DESeq
bat_genomeR. aegyptiacusGenome 2248.16 2519.92 1972.7 2310.71 2455.49 2131.73 2489.71 2626.24 2350.25

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4272.24 4418.87 4253.69 0.05 -0.01 -0.05
7h 3704.16 3721.06 3575.7 0.01 -0.05 -0.06
23h 4006.05 3127.63 4170.98 -0.36 0.06 0.42

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4272.24 3704.16 4006.05 -0.21 -0.09 0.11
Ebov 4418.87 3721.06 3127.63 -0.25 -0.5 -0.25
Marv 4253.69 3575.7 4170.98 -0.25 -0.03 0.22

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1251.13 1417.54 1339.22 0.18 0.1 -0.08
7h 1269.95 1266.92 1433.65 -0.0 0.17 0.18
23h 1162.68 1217.46 1383.91 0.07 0.25 0.18

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1251.13 1269.95 1162.68 0.02 -0.11 -0.13
Ebov 1417.54 1266.92 1217.46 -0.16 -0.22 -0.06
Marv 1339.22 1433.65 1383.91 0.1 0.05 -0.05